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2-Methoxyestradiol-d<sub>5</sub>

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12033S2
    2-Methoxyestradiol-d5

    2-ME2-d<sub>5sub>; NSC-659853-d<sub>5sub>

    		 Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite
    2-Methoxyestradiol-d5 is the deuterium labeled 2-Hydroxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6][7].
    2-Methoxyestradiol-d5

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